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Japanese Mushroom Extract Kills Off HPV In Cervical Cancer Cells
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A compound from a Japanese mushroom has been found to eradicate human papillomavirus (HPV) in cervical cancer cells, illuminating a potential treatment strategy against the disease that kills thousands of U.S. women every year.
Dr. Judith A. Smith, a researcher at the University of Texas and lead author of the new study, said that the mushroom extract active hexose correlated compound (AHCC) also appears to slow down tumor growth. "The results of this study were very encouraging," she said in a
press release. "This study, initiated in 2008, shows that by itself AHCC has the potential to treat the HPV infection.”
Virtually all cervical cancers are caused by
HPV. Vaccines like Gardasil and Ceravix have proven highly effective in preventing the infection, but they only protect against some strains. New treatment methods are therefore crucial to bringing down incidence and mortality rates.
The new study, which was presented at the Society of Gynecological Oncology’s annual meeting in Tampa, Fla. shows that AHCC appears to shut down the infection both in vitro and in vivo. First, Smith and colleagues tested the compound in cell cultures isolated from cervical cancer patients. They then treated an HPV mouse model with a supplement derived from the mushroom extract.
In both experiments, AHCC was shown to eradicate the virus within 90 days. This opens up a range of opportunities for oncologists and drug researchers, Smith said. "AHCC is a common, well tolerated nutritional supplement that has been used for decades in Japan,” she explained. “I am very excited to be pursuing a nutritional approach to trying to find a treatment for HPV infections."
Eliminating Cervical Cancer According to the
Centers for Disease Control and Prevention (CDC), about 4,000 women die from cervical cancer each year. Like cancers of the pancreas and ovaries, the disease is often diagnosed with an abysmal prognosis, as it tends to til it spreads to neighboring tissue through a nefarious process called metastasis. Still, prevention methods like Pap smears and HPV vaccines have led to a significant reduction in cases over the past decades.
Smith’s paper is the latest in a growing number of studies aimed at improving current treatment and prevention protocols for HPV and cervical cancer. Another example is a
review in
PLoS Medicine published earlier this year, in which researchers from Queen Mary University in London suggest that current screening practices should not be limited to younger women.
# `. d- P5 n2 b: X" k. H 香 菇是美味的食材，美國德薩斯州大學更發現，從香菇中提取的活性化合物（AHCC），能預防由人類乳頭瘤病毒（HPV）引致的癌症，包括子宮頸癌、肛門癌、喉癌、陰道和陰莖癌等，老鼠實驗更顯示，該種化合物可在九十日內清除HPV，相信將來可望取代預防HPV的疫苗。
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AHCC能增加人體內的樹突狀細胞、細胞激素的數量和活躍度，這可使身體有效預防感染，及阻止腫瘤增生，令人體的免疫系統對抗疾病。負責研究的德薩斯州大學醫學院專家表示，AHCC作為營養補充劑在日本已使用多年，對於今次發現該種成分能清除HPV感到鼓舞，希望將來能用作治療HPV感染，取代現時有副作用的藥物治療。0 H# ?' \+ f6 @: R L$ M6 T! ^
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香菇(Xiang Gu)
- P8 S5 x- j' ?3 {7 ?【别名】香蕈、合蕈、台蕈、台菌、雷惊蕈、戴沙、石蕈、椎蕈、香信、冬菇、菊花菇、香纹
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- h ^8 b, H: I【性味】味甘；性平；无毒。
; R$ C: L( j9 t/ u3 W8 G0 n# T+ W【归经】入肝；胃经。
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【功效】扶正补虚；健脾开胃；祛风透疹；化痰理气；解毒；抗癌。
4 n3 X* p V2 i+ L. W) f【主治】正气衰弱；神倦乏力；纳呆；消化不良；贫血；佝偻病；
高血压；
高脂血症；慢性肝炎；盗汗；小便不禁；水肿；麻疹透发不畅；
荨麻疹；毒菇中毒；肿瘤
6 l0 `( D E2 d, G y3 f3 U【用法用量】内服：煎汤，6-9g，鲜品15-30g。
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【注意】脾胃寒湿气滞者禁服。
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发表于 2014-4-2 23:30:42
楼主
发表于 2014-4-3 10:09:12
，学习了。
